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“Great”Jack C. tuần trước
Writing 15 pages literature review about medical topic
“I appreciate her efforts, commitment, and prfessionality as usual. It was not the first project and it will not be the last. Thank you for your help.”Abdulrahman 1 tháng trước
2+2 pages literature review, scientific writing
“Very cooperative! She is expert in research writing and I would hire her again for next projects.”Abdulrahman 1 tháng trước
Writing 10 pages of Literature review as a part of medical research
“Thank you Manjulata Devi S.@Manjusundru. You did great job. I'll hire you again.”Abdulrahman 1 tháng trước
Academic Article Writing
“She is very supportive in terms of updating the project as per requirements and a thorough professional”Jayesh K. 3 tháng trước
“very professional and approachable .”Manoj V. 3 tháng trước
Young ScientistSep 2014 - Sep 2017 (3 years)
Worked as Young Scientist (Principle Investigator) under startup grant scheme sponsored by SERB-Department of Science and Technology (DST), New Delhi, India, with the project entitled “Detection and expression of immunomodulatory and probiotic marker genes among Lactobacillus sp.”
Research AssociateMay 2013 - Jan 2014 (8 months)
Worked as Project Assistant Level-IV (Research Associate) (16th May 2013 to 27th Jan 2014), in an Indian Council of Medical Research (ICMR) funded project entitled “Rapid detection of probiotic lactic acid bacteria and assessing their suitability In Vivo system”. • Produced actionable information that improved the research data and published an article related to the project at "Probiotics and anti-microbial peptides journal".
Senior Research FellowOct 2008 - Jul 2012 (3 years)
Worked as a Ph.D Research Scholar with the Senior Research Fellowship (SRF) awarded by Council for Scientific and Industrial Research (CSIR), New Delhi. Ph.D. Thesis title: Molecular genetic studies of pediocin-like bacteriocin in Pediococcus, Lactobacillus and Enterococcus sp.”
Project AssistantNov 2004 - Sep 2007 (2 years)
• Worked with principal investigators to coordinate qualitative research under the host pathogen interaction of Helicobacter pylori. • Researched information regarding molecular characterization of Leptospira species and assisted the supervisors or professors with project pursuits. • Prepared materials for reports, presentations, and submission to peer-reviewed journal publications. • Analyzed acquired information and presented to professors.
PhD, Biotechnology2008 - 2012 (4 years)
Masters of Science, Microbiology2002 - 2004 (2 years)
Bachelor of Science (Microbiology, Genetics, Chemistry)1999 - 2002 (3 years)
PhD, Biotechnology (2013)University of Mysore
Young Scientist Award (2014)SERB- Department of Science and Technology, New Delhi
Các xuất bản
In vitro anti-inflammatory activity among probiotic Lactobacillus species......
Probiotic bacteria have the ability to alter immune response conferring treatment to inflammatory diseases. In the current study, probiotic Lactobacillus strains were subjected to adhesion to epithelial Caco-2 cells. Subsequently, gene expression of pro-and anti-inflammatory genes were studied under three stimulation.
Genetic Variation of pln Loci Among Probiotic..... with Antioxidant and Cholesterol-Lowering Ability
In the present study, 14 different plantaricin encoding genes of pln loci were studied and compared to available sequences from public domain database of probiotic Lactobacillus plantarum strains. Based upon the presence and absence of selected genes, pln locus was grouped into eight clusters. Further, quantitative real-time PCR (qRT-PCR) analysis for seven genes has discriminated the complex pln locus into five types which includes WCFS1, closely related to J51, J23, NC8, and a new E1 type.
Diversity and evolutionary aspects of mucin binding (MucBP).....through comparative genetic analysis
Mucin binding protein (Mub) of Lactobacillus plantarum- group (LPG) is considered as a potential marker gene due to its diversity and adherence property to host intestinal layer. The mub gene expression pattern noted by real-time PCR revealed 67.64 increased fold change in MTCC 9483 with four MucBP [login to view URL], the isolates with 3 and 2 MucBP repeats showed ∼4 and 2 enhanced expression, respectively.
Discrimination and divergence among Lactobacillus....probiotic functionalities from vegetable origin
As determined by nucleotide sequence analysis and bioinformatics Pfam database, the putative Fbp protein and Mub protein had shown variation. However, L. pentosus, L. plantarum subsp. argentoratensis and L. arizonensis isolates gave no amplicon for the tested marker genes. Selected cultures showed tolerance to simulated digestive fluids (20–85%), exhibited auto-aggregation (10–77%), cellular hydrophobicity (12–78%), and broad spectrum of anti-microbial activity.
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